Skip Navigation



Alcohol and Alcoholism Advance Access published online on December 15, 2006
Alcohol and Alcoholism, doi:10.1093/alcalc/agl091
This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
42/2/158    most recent
agl091v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by BUCKNAM, W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by BUCKNAM, W.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2006. Published by Oxford University Press on behalf of the Medical Council on Alcohol. All rights reserved
Received July 14, 2006
Revised August 18, 2006
Accepted September 5, 2006

Case Report

SUPPRESSION OF SYMPTOMS OF ALCOHOL DEPENDENCE AND CRAVING USING HIGH-DOSE BACLOFEN

WILLIAM BUCKNAM 1 *

1 No. 207, 5340 Plymouth Road, Ann Arbor, MI 48105, USA

* To whom correspondence should be addressed.
WILLIAM BUCKNAM, E-mail: wbucknam{at}hotmail.com


  Abstract

Aims: To further test whether the baclofen-induced suppression of motivation to consume alcohol in animals could be transposed to humans. Methods: A patient who had neither tolerated nor benefited from other alcohol treatment modalities was put on trial with baclofen on a dosage up to 140 mg/day. Results: The patient reported dramatic reduction in cravings for and preoccupation with alcohol. Conclusions: High-dose baclofen therapy was associated with complete and prolonged suppression of symptoms and consequences of alcohol-dependence.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Alcohol AlcoholHome page
L. Leggio
Understanding and Treating Alcohol Craving and Dependence: Recent Pharmacological and Neuroendocrinological Findings
Alcohol Alcohol., July 1, 2009; 44(4): 341 - 352.
[Abstract] [Full Text] [PDF]

Home page
 Alcohol AlcoholHome page
O. Ameisen
Gamma-Hydroxybutyrate (GHB)-Deficiency in alcohol-dependence?
Alcohol Alcohol., September 1, 2007; 42(5): 506 - 506.
[Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.