Alcohol and Alcoholism Advance Access published online on March 7, 2006
Alcohol and Alcoholism, doi:10.1093/alcalc/agl014
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1 Liver Unit, MP811, University of Southampton Medical School and Southampton University Hospitals Trust, Southampton, SO22 6PP, UK
* To whom correspondence should be addressed. Aims: To examine the hypothesis that patients who present in the UK to detoxification services differ from patients who present with severe alcohol-induced liver disease (ALD) with respect to severity of dependence on alcohol and other features of their drinking history. Methods: Levels of alcohol dependence were assessed in 34 patients with severe ALD, all of whom were cirrhotic, and 34 subjects from a residential alcohol detox centre in Southampton using the Severity of Alcohol Dependence Questionnaire (SADQ). During interview, various aspects of participants' alcohol consumption were recorded, including total monthly consumption, whom they usually drank with and where, and, if applicable, what caused them to start drinking heavily. Social circumstances were also noted, including participants' employment and marital status. Results: Among ALD patients, 58% scored none/mild on the SADQ, 32% moderate and 9% severe. In contrast, 76% of the detox group were graded severe and 34% moderate (P < 0.001). ALD patients were also significantly older, had lower scores on the Alcohol Use Disorders Identification Test, tended to drink less alcohol, were more likely to be in a stable relationship, were less likely to be unemployed and gave different reasons for starting to drink heavily. The ALD group were most likely to have started drinking heavily for social reasons, whereas subjects in the detox group were most likely to have started drinking heavily as a result of relationship or money problems. Conclusion: Patients attending a liver unit and patients admitted to a detoxification unit were separate but overlapping populations of alcohol misusers. Perhaps these two populations of alcohol misusers are likely to require different approaches for effective detection, intervention and treatment.
Received October 24, 2005
Revised February 2, 2006
Accepted February 3, 2006
Article
SEVERE ALCOHOL-INDUCED LIVER DISEASE AND THE ALCOHOL DEPENDENCE SYNDROME
STEWART SMITH 1,
JOANNA WHITE 1,
CHRIS NELSON 1,
MARIANNE DAVIES 1,
JOANNE LAVERS 1,
and
NICK SHERON 1 *
NICK SHERON, E-mail: nick.sheron{at}soton.ac.uk
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