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Alcohol and Alcoholism Advance Access published online on October 21, 2005

Alcohol and Alcoholism, doi:10.1093/alcalc/agh224
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© The Author 2005. Published by Oxford University Press on behalf of the Medical Council on Alcohol. All rights reserved
Received May 16, 2005
Revised September 28, 2005
Accepted September 29, 2005


Article

ECONOMIC EVALUATION OF INTERVENTIONS FOR PROBLEM DRINKING AND ALCOHOL DEPENDENCE: DO WITHIN-FAMILY EXTERNAL EFFECTS MAKE A DIFFERENCE?

DUNCAN MORTIMER 1* and LEONIE SEGAL 1

1 Centre for Health Economics, Faculty of Business and Economics, Monash University, VIC 3800, Australia

* To whom correspondence should be addressed.
DUNCAN MORTIMER, E-mail: duncan.mortimer{at}buseco.monash.edu.au


   Abstract

Aims: To propose methods for the inclusion of within-family external effects in clinical and economic evaluations. To demonstrate the extent of bias due to the exclusion of within-family external effects when measuring the relative performance of interventions for problem drinking and alcohol dependence. Methods: The timing and magnitude of treatment effects are modified to accommodate the external health-related quality of life impact of having a problem or dependent drinker in the family home. Results: The inclusion of within-family external effects reduces cost per QALY estimates of interventions for problem drinking and alcohol dependence thereby improving the performance of all evaluated interventions. In addition, the inclusion of within-family external effects improves the relative performance of interventions targeted at those with moderate-to-severe alcohol dependence as compared to interventions targeted at less severe alcohol problems. Conclusions: Failure to take account of external effects in clinical and economic evaluations results in an uneven playing field. Interventions with readily quantifiable health benefits (where social costs and benefits are predominantly comprised of private costs and benefits) are at a distinct advantage when competing for public funding against interventions with quantitatively important external effects.


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