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Alcohol and Alcoholism Advance Access originally published online on December 4, 2007
Alcohol and Alcoholism 2008 43(2):174-179; doi:10.1093/alcalc/agm144
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Copyright © The Author 2007. Published by Oxford University Press on behalf of the Medical Council on Alcohol.

Review

Wernicke's encephalopathy revisited

Translation of the case history section of the original manuscript by Carl Wernicke ‘Lehrbuch der Gehirnkrankheiten fur Aerzte and Studirende’ (1881) with a commentary

Allan D. Thomson1,4, Christopher C. H. Cook2, Irene Guerrini1, Donna Sheedy3, Clive Harper3 and E. Jane Marshall4,*

1 Molecular Psychiatry Laboratory, Windeyer Institute of Medical Science, Dept. of Mental Health Sciences, Royal Free and University College London Medical School, 46 Cleveland Street, London W1 T 4JF, UK
2 County Durham and Darlington Priority Services NHS Trust (Postal address: Department of Theology and Religion, Durham University, Abbey House, Palace Green, Durham DH1 3RS)
3 Department of Pathology (D06), University of Sydney, NSW 2006 Australia
4 National Addiction Centre, Box 048, Institute of Psychiatry, Kings College London, De Crespigny Park, London SE5 8AF, UK

* Author to whom correspondence should be addressed at: National Addiction Centre, Box 048, Institute of Psychiatry, Kings College London, De Crespigny Park, London SE5 8AF, UK. Tel: 0044 (0) 203228 2345; Fax: 0044 (0) 203228 2349; E-mail: jane.marshall{at}slam.nhs.uk

Received 27 April 2007; in revised form 4 June 2007; in revised form 2 August 2007; accepted 4 September 2007


  Abstract

Aims: A translation into English of the case history section of Carl Wernicke's original manuscript of 1881, with a discussion on its relevance for clinicians today. Methods: A copy of Carl Wernicke's original German text was obtained by one of the authors (CCHC) and translated into English from the old German by a professional translator. Results: The translation was subsequently agreed by native German speaking referees, and minor changes made. Conclusions: The authors studied the translation in detail and concluded that Wernicke's description had stood the test of time. The diagnosis of Wernicke's Encephalopathy remains a clinical one.


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