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Alcohol and Alcoholism Advance Access originally published online on November 18, 2004
Alcohol and Alcoholism 2005 40(1):1; doi:10.1093/alcalc/agh109
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Alcohol & Alcoholism Vol. 40, No. 1 © Medical Council on Alcohol 2005; all rights reserved

PREFACE TO THE SPECIAL ISSUE ARTICLES ON ALCOHOL AND CANNABIS

GIANCARLO COLOMBO*

C.N.R. Institute of Neuroscience, Section of Cagliari, Cagliari, Italy

* Correspondence: C.N.R. Institute of Neuroscience, Section of Cagliari, Viale Diaz, 182, I-09126 Cagliari (CA), Italy. Tel.: +39 070 302227; Fax: +39 070 302076; E-mail: colomb@unica.it

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In recent years, accumulating lines of experimental evidence have suggested that the endocannabinoid system is a major player among the neurotransmitter systems involved in the neurobiology of alcohol. This progress has been originated from a series of important findings, including, among others, the discovery and the subsequent cloning of specific receptors for cannabinoids in the CNS, the identification of endogenous ligands and enzymes involved in ligand biosynthesis and inactivation, the synthesis of potent agonists and . . . [Full Text of this Article]


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