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Alcohol and Alcoholism Vol. 37, No. 6, pp. 609-612, 2002
© 2002 Medical Council on Alcohol

ANXIETY AS A PREDICTOR OF RELAPSE IN DETOXIFIED ALCOHOL-DEPENDENT PATIENTS

Ulrike Willinger*, Elisabeth Lenzinger, Kurt Hornik1, Gabriele Fischer, Georg Schönbeck, Harald N. Aschauer and Kurt Meszaros On Behalf Of The European Fluvoxamine In Alcoholism Study Group

Department of General Psychiatry, University Hospital for Psychiatry, Vienna and
1 University of Economics, Vienna, Austria

Received 6 February 2002; first review notified 22 May 2002; accepted 10 June 2002

Aims: To evaluate the impact of mood, affect, and personality on predicting relapse in detoxified alcohol-dependent patients to uncontrolled drinking during a 1-year treatment study. Methods: A total of 521 patients with a DSM-III-R diagnosis of alcohol dependence, excluding those with major depressive disorder, took part in a European multicentre study (11 centres in the United Kingdom, Irish Republic, Switzerland, and Austria). Depressive symptoms were assessed using the Hamilton Depression Scale, whereas symptoms of anxiety were measured using the ‘STAI-X2’ of the self-rating scale State–Trait Anxiety Inventory and personality traits were measured by the Tridimensional Personality Questionnaire. Results: High anxiety as a stable trait, and personality traits such as high novelty seeking and low harm avoidance covering exploratory excitability, impulsiveness, extravagance, disorderliness and uninhibited optimism, predicted relapse. Conclusions: These measures could have a direct clinical application for predicting relapse to uncontrolled drinking in male and female detoxified alcohol-dependent patients. The findings indicate the importance of additional therapeutic treatment.


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