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Alcohol and Alcoholism Vol. 36, No. 4, pp. 314-317, 2001
© 2001 Medical Council on Alcoholism

The effect of long-term ethanol feeding on Brucella melitensis infection of rats

Zeki Yumuk*,, Sitki Ozdemirci1,, B. Faruk Erden1, and Volkan Dundar

Departments of Microbiology and
1 Pharmacology, Kocaeli University Faculty of Medicine, Kocaeli, Turkey

Received 1 November 2000; first review notified 2 February 2001; accepted 15 February 2001

The adverse effects of ethanol on Brucella melitensis have not been studied previously. In this study, a new model of B. melitensis infection was used in the setting of chronic ethanol administration in rats. It was found that the chronically ethanol-receiving rats exposed to B. melitensis infection had significantly greater numbers of B. melitensis in their spleen and liver than the rats in the control group.


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