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Alcohol and Alcoholism Vol. 36, No. 4, pp. 292-297, 2001
© 2001 Medical Council on Alcoholism

Ethanol facilitation of short-term memory in adult rats with a disturbed circadian cycle

P. Mikolajczak*,, I. Okulicz-Kozaryn, M. Nowaczyk and E. Kaminska

Department of Pharmacology, K. Marcinkowski University of Medical Sciences in Poznan, Fredry 10, 61-701 Poznan, Poland

Received 5 June 2000; first review notified 29 December 2000; accepted 24 January 2001

The aim of this study was to evaluate the effect of 3-month ethanol treatment on olfactory social memory test performance using two inter-exposure intervals [30 min: short-term recognition (STR); or 120 min: long-term recognition (LTR)] in adult rats with a disturbed circadian cycle (DCC). Ethanol treatment both in ethanol-preferring and -non-preferring groups improved the STR task compared to control rats. However, LTR procedure triggered the opposite tendency. Moreover, no differences between control rats with DCC and those with normal diurnal rhythm in STR and LTR paradigms were observed. Our results suggest that, under some conditions, alcohol facilitates short-term memory in adult rats.


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