Alcohol and Alcoholism Vol. 36, No. 3, pp. 185-188, 2001
© 2001 Medical Council on Alcoholism
EDITORIAL COMMENTARY
Moderate alcohol consumption as a cardiovascular risk factor: the role of homocysteine and the need to re-explain the ‘French Paradox’
Cardiff and Vale NHS Trust, Biomedical Research Laboratory, Whitchurch Hospital, Cardiff CF14 7XB, UK
On 189–192 of this issue of Alcohol and Alcoholism, Bleich et al. (2001) report the results of an experimental study demonstrating that consumption of moderate amounts of alcohol (30 g per day) for 6 weeks by healthy social drinkers increases the circulating concentration of the cardiovascular risk factor homocysteine (HCy), irrespective of the type of the alcoholic beverage consumed (beer, red wine or spirit). Given the current emphasis on the cardiovascular health benefits of moderate alcohol consumption, this study merits the attention of the medical community, public health authorities and political decision-makers.
It must, however, be emphasized from the outset that this, the first of its kind, is a preliminary study in which Dr Stephan Bleich and his colleagues have assessed only 60 subjects, who were further divided into four groups of 15 each. Numbers are therefore very small indeed, and the need to replicate the findings cannot
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