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Alcohol and Alcoholism 2006 41(2):119-120; doi:10.1093/alcalc/agl003
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© The Author 2006. Published by Oxford University Press on behalf of the Medical Council on Alcohol. All rights reserved

INVITED EDITORIAL

DISULFIRAM, COCAINE, AND ALCOHOL: TWO OUTCOMES FOR THE PRICE OF ONE?

MICHAEL GOSSOP1,* and KATHLEEN M. CARROLL2

1 National Addiction Centre, Maudsley Hospital/Institute of Psychiatry, King's College London, London SE5 8BB, UK and 2 Division of Substance Abuse, Yale University School of Medicine, West Haven CT 06516, USA

* Author to whom correspondence should be addressed at: E-mail: M.Gossop@iop.kcl.ac.uk.

The first 10% of the full text of this article appears below.

The concurrent abuse of cocaine and alcohol is a common phenomenon, and is increasingly recognized as a difficult clinical issue. Several effective pharmacotherapies for substance dependence disorders have been identified, though the search for an effective pharmacotherapy for cocaine dependence has proved difficult. However, it has been suggested that disulfiram may offer a promising treatment option.

The randomized, placebo-controlled study of Carroll et al. (2004)Go provides some of the strongest evidence to date regarding the effectiveness of disulfiram treatment in reducing cocaine use. In a large . . . [Full Text of this Article]


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