Alcohol and Alcoholism Vol. 38, No. 1, pp. 93-94, 2003
© 2003 Medical Council on Alcohol
LETTER TO THE EDITOR
INFLUENCE OF GENETIC ADMIXTURE ON POLYMORPHISMS OF ALCOHOL-METABOLIZING ENZYMES: ANALYSES OF MUTATIONS ON THE CYP2E1, ADH2, ADH3 AND ALDH2 GENES IN A MEXICANAMERICAN POPULATION LIVING IN THE LOS ANGELES AREA
Departments of Pathology and
1 Psychiatry, Harbor-UCLA Medical Center, Torrance, CA, USA
Received 12 June 2002; first review notified 12 August 2002; accepted 1 September 2002
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In pre-Columbian times, the population of Mexico was totally indigenous or Amerindian. When Columbus arrived in the New World, and Cortez marched from Vera Cruz into the Valley of Mexico, a whole new element of genes was introduced into the existing populations. They were a diverse set of genes reflecting Europe and Africa. Today, Mexican Americans are estimated to be derived from Native Americans by 31%, Spanish
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