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Alcohol and Alcoholism Advance Access originally published online on August 4, 2008
Alcohol and Alcoholism 2008 43(6):647-649; doi:10.1093/alcalc/agn050
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© The Author 2008. Published by Oxford University Press on behalf of the Medical Council on Alcohol. All rights reserved

Central Pontine and Extrapontine Myelinolysis After Alcohol Withdrawal

Bora Yoon, Yong-Soo Shim and Sung-Woo Chung*

Department of Neurology, College of Medicine, The Catholic University of Korea, Korea

* Corresponding author: Department of Neurology, The Catholic University of Korea, Our Lady of Mercy Hospital 665, Bupyeong 6-dong, Bupyeong-gu, Incheon, Korea, 403-720. Tel: +82-32-510-5874; Fax: +82-32-519-7336; E-mail: cnspns{at}catholic.ac.kr

Received 3 March 2008; first review notified 2 May 2008; in revised form 15 May 2008; accepted 28 May 2008; advance access publication 4 August 2008


  Abstract

Central pontine myelinolysis (CPM) and extrapontine myelinolysis (EPM) are well-recognized syndromes that are related to various conditions such as rapid correction of hyponatremia and chronic alcoholism. We report a very case of a patient with dysarthria, dysphagia and psychiatric symptoms including abnormal behavior starting after alcohol withdrawal, with radiological evidence of CPM and EPM. There was little improvement in the dysarthria or psychiatric symptoms in the first month.


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