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Alcohol and Alcoholism Advance Access originally published online on August 8, 2005
Alcohol and Alcoholism 2005 40(6):563-568; doi:10.1093/alcalc/agh191
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© The Author 2005. Published by Oxford University Press on behalf of the Medical Council on Alcohol. All rights reserved

CURRENT ALCOHOL USE IS ASSOCIATED WITH A REDUCED RISK OF HOT FLASHES IN MIDLIFE WOMEN

CHRISSY SCHILLING1, LISA GALLICCHIO2, SUSAN R. MILLER3, JANICE K. BABUS1, LYNN M. LEWIS1, HOWARD ZACUR3 and JODI A. FLAWS1,*

1 Department of Epidemiology and Preventive Medicine, Program in Toxicology, University of Maryland School of Medicine, 660 West Redwood Street, Howard Hall Room 133, Baltimore, MD 21201, USA, 2 Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA and 3 Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA

* Author to whom correspondence should be addressed at: Tel.: +1 410 706 3606; Fax: +1 410 706 1503; Email: jflaws{at}epi.umaryland.edu

(Received 15 June 2005; first review notified 1 July 2005; accepted in final revised form 12 July 2005)

Aims: To examine the relation between current alcohol use, estradiol, estrone, and testosterone levels, and hot flashes in midlife women using a case–control study design. Methods: Cases were midlife women (45–54 years) who reported ever experiencing hot flashes. Controls were midlife women (45–54 years) who reported never experiencing hot flashes. Each participant completed a questionnaire and provided a blood sample that was used to measure estradiol, estrone, and testosterone levels by enzyme-linked immunosorbent assay. Results: The results indicate that current alcohol use (at least one day per month) was significantly associated with a reduced risk of hot flashes compared to non-use of alcohol, independent of age and smoking habits. The hot flashes experienced by current alcohol users were less severe and less frequent than those experienced by non-users of alcohol. Further, current alcohol users had similar levels of estradiol, estrone, and testosterone compared to non-users of alcohol. Conclusions: These data suggest that current alcohol use is associated with a reduced risk of any, severe, and frequent hot flashes in midlife women by a mechanism that may not include changes in sex steroid hormone levels.


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Home page
 Obstet GynecolHome page
C. J. Cochran, L. Gallicchio, S. R. Miller, H. Zacur, and J. A. Flaws
Cigarette Smoking, Androgen Levels, and Hot Flushes in Midlife Women
Obstet. Gynecol., November 1, 2008; 112(5): 1037 - 1044.
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