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Alcohol and Alcoholism Advance Access originally published online on August 15, 2005
Alcohol and Alcoholism 2005 40(6):549-555; doi:10.1093/alcalc/agh192
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© The Author 2005. Published by Oxford University Press on behalf of the Medical Council on Alcohol. All rights reserved

ECONOMIC EVALUATION OF INTERVENTIONS FOR PROBLEM DRINKING AND ALCOHOL DEPENDENCE: COST PER QALY ESTIMATES

DUNCAN MORTIMER* and LEONIE SEGAL

Centre for Health Economics, Faculty of Business and Economics, Monash University, VIC 3800, Australia

* Author to whom correspondence should be addressed at: Tel.: +613 9905 0735; Fax: +613 9905 8344; E-mail: duncan.mortimer{at}buseco.monash.edu.au

(Received 16 May 2005; first review notified 3 June 2005; in final revised form 26 June 2005; accepted 13 July 2005)

Aims: To compare the performance of competing and complementary interventions for prevention or treatment of problem drinking and alcohol dependence. To provide an example of how health maximising decision-makers might use performance measures such as cost per quality adjusted life year (QALY) league tables to formulate an optimal package of interventions for problem drinking and alcohol dependence. Methods: A time-dependent state-transition model was used to estimate QALYs gained per person for each intervention as compared to usual care in the relevant target population. Results: Cost per QALY estimates for each of the interventions fall below any putative funding threshold for developed economies. Interventions for problem drinkers appear to offer better value than interventions targeted at those with a history of severe physical dependence. Conclusions: Formularies such as Australia's Medicare should include a comprehensive package of interventions for problem drinking and alcohol dependence.


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