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Alcohol and Alcoholism Vol. 37, No. 6, pp. 618-621, 2002
© 2002 Medical Council on Alcohol

WINE CONSUMPTION IS NOT ASSOCIATED WITH A DECREASED RISK OF ALCOHOLIC CIRRHOSIS IN HEAVY DRINKERS

Stéphanie Pelletier1, Emmanuel Vaucher2, Rachid Aider3, Sandrine Martin1, Pascal Perney4, Jean Louis Balmès1 and Bertrand Nalpas1,5,*

1 Service d’Hépatogastroentérologie et Alcoologie, CHU Caremeau, Nîmes,
2 Service d’Hépatogastroentérologie, Centre Hospitalier, Narbonne,
3 Centre de soins spécialisés, Notre-Dame de la Rouvière,
4 Service de Médecine Interne, CHU St Eloi, Montpellier and
5 INSERM U 370, Paris, France

Received 22 March 2002; first review notified 12 June 2002; accepted 28 June 2002

— Aims: While it was thought that all alcoholic beverages share a similar liver toxicity when drunk at a high level, recent epidemiological surveys have suggested that wine drinking might decrease the risk of alcoholic cirrhosis in heavy drinkers. Therefore, we performed a study aiming to analyse the type and the intake levels of alcoholic beverages in heavy drinkers according to the severity of the liver disease. Methods: This is a case–control study enrolling 42 cirrhotic and 60 non-cirrhotic patients. Liver status was assessed using clinical, biological, histological and ultrasonographic procedures. Alcohol consumption was recorded using the Lifetime Drinking History method. Results: We did not find any significant differences in total alcohol consumption between cases and controls and, moreover, in our series, the relative percentage of pure alcohol drunk in wine was significantly higher in cirrhotic, than in non-cirrhotic, patients. Conclusions: Our results confirm that the absence of a link between the type of alcoholic beverage and the occurrence of cirrhosis is still valid.


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