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Alcohol and Alcoholism Vol. 36, No. 5, pp. 393-400, 2001
© 2001 Medical Council on Alcohol

ALCOHOLIC POLYNEUROPATHY: A CLINICAL AND EPIDEMIOLOGICAL STUDY

Giovanni Vittadini,*, Michelangelo Buonocore1, Giuseppe Colli2, Marta Terzi2, Rodolfo Fonte and Giampiero Biscaldi2

Alcohol-dependency Unit and
1 Unit of Clinical Neurophysiology, Fondazione ‘S. Maugeri’, Clinica del Lavoro e della Riabilitazione, IRCCS, Istituto Scientifico di Pavia, Via A. Ferrata 4, 27100 Pavia and
2 Department of Preventive Occupational and Community Health, University of Pavia School of Medicine, Via S. Boezio 13, 27100 Pavia, Italy

Received 25 September 2000; in revised form 26 February 2001; accepted 14 March 2001

— In the present study, we investigated the frequency of polyneuropathy in a sample of 296 alcoholics who were admitted to the ‘S. Maugeri’ Medical Centre for detoxification from October 1997 to November 1999. Results revealed a high frequency of polyneuropathy in the sample under study. The disorder was often clinically asymptomatic and demonstrable only on electroneurographic investigation. Significant correlations were found between polyneuropathy, the duration of alcoholism, the type of alcoholic beverage consumed (wine) and the presence of liver disease and macrocytosis.


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