Skip Navigation

This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (3)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Yamamoto, M.
Right arrow Articles by Götz, M. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Yamamoto, M.
Right arrow Articles by Götz, M. E.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Alcohol and Alcoholism Vol. 36, No. 1, pp. 70-74, 2001
© 2001 Medical Council on Alcoholism

Immunoreactivity of cAMP response element binding protein is not altered in the post-mortem cerebral cortex or cerebellum of alcoholics

Megumi Yamamoto*, Sabine Pohli, Nuria Durany, Hiroki Ozawa1, Toshikazu Saito1, Karl W. Boissl2, Robert Zöchling2, Peter Riederer, Jobst Böning and Mario E. Götz

Clinical Neurochemistry, Department of Psychiatry and Psychotherapy, University of Würzburg, Füchsleinstrasse 15, 97080 Würzburg, Germany,
1 Department of Neuropsychiatry, Sapporo Medical University, S.1, W. 16, Chuo-ku, Sapporo, 060-8543 Japan and
2 State Hospital of Psychiatry and Neurology, Mauer, A-3362 Mauer, Austria

Received 28 March 2000; in revised form 19 June 2000; accepted 8 July 2000

— We examined amounts of cAMP response element binding protein (CREB) and its phosphorylated form in post-mortem frontal and temporal cortices and cerebella from alcoholics and controls by immunoblotting. No significant differences were observed in the levels of these proteins in each brain region, suggesting that the assumed neuroadaptations to chronic ethanol intake may not be reflected by quantitative alterations of CREB in alcoholic brain.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J. Neurosci.Home page
B. T. Hope, D. Nagarkar, S. Leonard, and R. A. Wise
Long-Term Upregulation of Protein Kinase A and Adenylate Cyclase Levels in Human Smokers
J. Neurosci., February 21, 2007; 27(8): 1964 - 1972.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.