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© 1994 Medical Council on Alcohol


other

7-OHDPAT AND ALCOHOL CONSUMPTION, WITHDRAWAL AND DISCRIMINATIVE STIMULUS PROPERT IN RATS

T. F. MEERT and G. H. C. CLINCKE

Department of Neuropsychopharmacology, Janssen Research Foundation B-2340 Beerse, Belgium

Received 1 June 1994; A senes of experiments was performed, which indicated that 7-OHDPAT is only active in rats that are still in the dynamic phase of the development of a high and stable level of alcohol preference and in a dnig discrimination test procedure, but not in rats with a matured preference for 3% alcohol. These data may point to a limited use of 7-OHDPAT in conditions of alcohol misuse and dependence.


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