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© 1994 Medical Council on Alcohol

other

ACUTE ETHANOL INCREASES TAURINE BUT NEiTHER GLUTAMATE NOR GABA IN THE NUCLEUS ACCUMBENS OF MALE RATS: A MICRODIALYSIS STUDY

A. DAHCHOUR, E. QUERTEMONT and P. DE WITTE

Laboratoiré de Psychobiologie, Université de Louvain, 1 Place Croix du Sud B-1348 Louvain-la-Neuve, Belgium

Received 1 June 1994; The effects of acute inu administration of ethanol (1–3 g/kg body wt) on the extracellular concentrations of glutamate (GLU), taunne (TAU) and {gamma}aminobutync acid (GABA) in rat brain nucleus accumbens were studied by the microdialysis technique coupled to HPLC-EC detection. Levels of GLU and GABA were not affected by ethanol, whereas those of TAU were increased by doses of the drug of 2–3 g/kg.


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