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© 1991 Medical Council on Alcohol


research-article

COMPARISON OF QUESTIONNAIRE AND BIOCHEMICAL MARKERS TO DETECT ALCOHOL ABUSE IN A WEST INDIAN POPULATION

B. PILEIRE, J. BREDENT-BANGOU and M. VALENTINO

Centre Hospitalier Regional et Universitaire, Laboratoire de Biochimie BP 465, Pointe-à-Pitre-Abymes, 97110 Guadeloupe, French Antilles

Received 10 February 1990; first review notified 8 January 1991; accepted 29 January 1991

This study bears upon the respective validity of biochemical markers and questionnaires to detect alcohol abuse in a population with a high rate of alcohol-linked neurological complications. GammaGT and apoprotein AII were the most powerful of eight studied biochemical markers in detecting two-thirds of excessive drinkers. The CAGE questionnaire identified 74% of moderate drinkers and 94% of excessive drinkers with a life style and patterns of alcohol consumption different from previously tested target populations. The joint association of the CAGE questionnaire and apoprotein AII detected more than 9 out of 10 moderate or excessive drinkers defined on the basis of a quantity-frequency grid


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