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© 1991 Medical Council on Alcohol

research-article

RED CELL CAESIUM, LITHIUM AND SELENIUM IN ABSTINENT ALCOHOLICS

F. M. CORRIGAN*, J. A. O. BESSON{dagger} and N. I. WARD{ddagger}

*Argyll & Bute Hospital Lochgilphcnd, Argyll Guildford, Surrey, U.K.
{dagger}Department of Mental Health, University of Aberdeen Guildford, Surrey, U.K.
{ddagger}Department of Chemistry, University of Surrey Guildford. Surrey, U.K.

Received 11 May 1990; first review notified 18 December 1990; accepted 14 April 1991

Using inductively coupled plasma source mass spectrometry, we have studied the red cell element concentrations of alcoholic subjects with different periods of abstinence before testing We found consistently elevated red cell caesium concentrations and also reduced red cell selenium concentrations. These may represent persistent abnormalities in oxidation/antioxidation mechanisms, and red cell caesium in particular may be a long-term marker of alcohol dependence Erythrocyte lithium, cerium and boron concentrations were also reduced in the abstinent alcoholic groups


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