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© 1989 Medical Council on Alcohol

other

INCREASE IN SYNAPTOSOMAL ACIDIC PHOSPHOLIPIDS AFTER INTERMITTENT BUT NOT CONTINUOUS ETHANOL EXPOSURE

LENA GUSTAVSSON* and CHRISTER ALLING

Department of Psychiatry and Neurochemistry, Lund University P.O. Box 638, S-220 06 Lund, Sweden

*Author for correspondence

Received 1 February 1989; accepted 13 February 1989

The aim of this study was to compare the effects of different ethanol administration procedures on synaptosomal concentrations of acidic phospholipids. The concentrations of phosphatidylinositol and phosphatidylserine were significantly increased after intermittent ethanol exposure for one week but were unaltered after one or three weeks of continuous ethanol administration. The results indicate the importance of drinking pattern for changes in synaptosomal acidic phospholipids.


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